New Strategies and Paradigm for Drug Target Discovery: A Special Focus on Infectious Diseases Tuberculosis, Malaria, Leishmaniasis, Trypanosomiasis and Gastritis
Nageswara R.R. Neelapu, Ravi C.P.K. Srimath-Tirumala-Peddinti, Deepthi Nammi and Amita C.M. Pasupuleti
Affiliation: Department of Biochemistry & Bioinformatics, School of Life Sciences, GITAM Institute of Science, GITAM University, Rushikonda Campus, Visakhapatnam -530045, (AP), India.
Keywords: Drug targets, Helicobacter pylori, infectious diseases, Leishmania, Mycobacterium tuberculosis, new paradigm,
Plasmodium falciparum, Trypanosoma.
The discovery and exploitation of new drug targets is a key focus for both the pharmaceutical industry and academic
research. To provide an insight into trends in the exploitation of new drug targets, we have analysed different
methods during the past six decades and advances made in drug target discovery. A special focus remains on different
methods used for drug target discovery on infectious diseases such as Tuberculosis, Gastritis, Malaria, Trypanosomiasis
and Leishmaniasis. We herewith provide a paradigm that is can be used for drug target discovery in the near future.
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