Infectious Disorders - Drug Targets

(Formerly Current Drug Targets - Infectious Disorders)

Jean-Marc Sabatier  
Laboratoire ERT 62 'Ingénierie des peptides à visée thérapeutique' 
Université de la Méditerranée
Faculté de Médecine Nord
Boulevard Pierre Dramard
13916 - MARSEILLE, Cedex 20


New Strategies and Paradigm for Drug Target Discovery: A Special Focus on Infectious Diseases Tuberculosis, Malaria, Leishmaniasis, Trypanosomiasis and Gastritis

Author(s): Nageswara R.R. Neelapu, Ravi C.P.K. Srimath-Tirumala-Peddinti, Deepthi Nammi and Amita C.M. Pasupuleti

Affiliation: Department of Biochemistry & Bioinformatics, School of Life Sciences, GITAM Institute of Science, GITAM University, Rushikonda Campus, Visakhapatnam -530045, (AP), India.

Keywords: Drug targets, Helicobacter pylori, infectious diseases, Leishmania, Mycobacterium tuberculosis, new paradigm, Plasmodium falciparum, Trypanosoma.


The discovery and exploitation of new drug targets is a key focus for both the pharmaceutical industry and academic research. To provide an insight into trends in the exploitation of new drug targets, we have analysed different methods during the past six decades and advances made in drug target discovery. A special focus remains on different methods used for drug target discovery on infectious diseases such as Tuberculosis, Gastritis, Malaria, Trypanosomiasis and Leishmaniasis. We herewith provide a paradigm that is can be used for drug target discovery in the near future.

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Article Details

Page: [352 - 364]
Pages: 13
DOI: 10.2174/1871526514666140321110312