Bu₃SnH Assisted Radical Cyclization Towards the Synthesis of Pyrimidine-annulated Spirocyclic and [6,6] Fused Sulfur Heterocycles

Title:Bu₃SnH Assisted Radical Cyclization Towards the Synthesis of Pyrimidine-annulated Spirocyclic and [6,6] Fused Sulfur Heterocycles

Volume: 11 Issue: 7

Author(s): K.C. Majumdar, P.K. Maji and S.K. Chattopadhayay

Affiliation:

Keywords: 5-exo-Cyclisation, , 6-endo Cyclization, AIBN, Pyrimidine, sulfur heterocycles, Tributyltin hydride, Radical reaction.

Abstract: Pyrimidine annulated sulfur heterocycles have been synthesized through tributyltin hydride-mediated radical reaction. This gave straight forward synthesis of tricyclic compound as well as spiro heterocyclic compounds. The reactions have been simple, straight forward and have been carried out in mild conditions.

Cite this article as:

Majumdar K.C., Maji P.K. and Chattopadhayay S.K., Bu₃SnH Assisted Radical Cyclization Towards the Synthesis of Pyrimidine-annulated Spirocyclic and [6,6] Fused Sulfur Heterocycles, Letters in Organic Chemistry 2014; 11 (7) . https://dx.doi.org/10.2174/1570178611666140318010053