Letters in Organic Chemistry

Miguel Yus  
Universidad de Alicante Apdo
Alicante
Spain

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Bu3SnH Assisted Radical Cyclization Towards the Synthesis of Pyrimidine-annulated Spirocyclic and [6,6] Fused Sulfur Heterocycles

Author(s): K.C. Majumdar, P.K. Maji and S.K. Chattopadhayay

Affiliation: Department of Chemistry University of Kalyani, Kalyani-741235. W.B. India.

Keywords: 5-exo-Cyclisation, , 6-endo Cyclization, AIBN, Pyrimidine, sulfur heterocycles, Tributyltin hydride, Radical reaction.

Graphical Abstract:


Abstract:

Pyrimidine annulated sulfur heterocycles have been synthesized through tributyltin hydride-mediated radical reaction. This gave straight forward synthesis of tricyclic compound as well as spiro heterocyclic compounds. The reactions have been simple, straight forward and have been carried out in mild conditions.

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Article Details

VOLUME: 11
ISSUE: 7
Page: [487 - 492]
Pages: 6
DOI: 10.2174/1570178611666140318010053