Bu3SnH Assisted Radical Cyclization Towards the Synthesis of Pyrimidine-annulated Spirocyclic and [6,6] Fused Sulfur Heterocycles
Pyrimidine annulated sulfur heterocycles have been synthesized through tributyltin hydride-mediated radical
reaction. This gave straight forward synthesis of tricyclic compound as well as spiro heterocyclic compounds. The reactions
have been simple, straight forward and have been carried out in mild conditions.
Keywords: 5-exo-Cyclisation, , 6-endo Cyclization, AIBN, Pyrimidine, sulfur heterocycles, Tributyltin hydride, Radical reaction.
Rights & PermissionsPrintExport