Letters in Organic Chemistry

Gwilherm Evano
Free University of Brussels
Brussels
Belgium

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Bu3SnH Assisted Radical Cyclization Towards the Synthesis of Pyrimidine-annulated Spirocyclic and [6,6] Fused Sulfur Heterocycles

Author(s): K.C. Majumdar, P.K. Maji, S.K. Chattopadhayay.

Graphical Abstract:


Abstract:

Pyrimidine annulated sulfur heterocycles have been synthesized through tributyltin hydride-mediated radical reaction. This gave straight forward synthesis of tricyclic compound as well as spiro heterocyclic compounds. The reactions have been simple, straight forward and have been carried out in mild conditions.

Keywords: 5-exo-Cyclisation, , 6-endo Cyclization, AIBN, Pyrimidine, sulfur heterocycles, Tributyltin hydride, Radical reaction.

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Article Details

VOLUME: 11
ISSUE: 7
Year: 2014
Page: [487 - 492]
Pages: 6
DOI: 10.2174/1570178611666140318010053
Price: $58