Combinatorial Chemistry & High Throughput Screening

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A Convenient Synthesis of 2-Imino-1,3-Thiazine-4-One Derivatives from the Reaction of Primary Amines and Phenyl Isothiocyanate in the Presence of Acryloyl Chloride

Author(s): Amin Zolali, Farough Nasiri and Sonia Omid-Niakan

Affiliation: Department of Chemistry, Faculty of Science, University of Kurdistan, Sanandaj, Iran.

Keywords: 1, 3-Thiazine, dithiocarbamate, MCRs, multicomponent, one-pot.

Abstract:

An efficient, one-pot and three-component synthesis of biologically important heterocyclic compounds is described from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride at room temperature without the need to use any catalyst.

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Article Details

VOLUME: 17
ISSUE: 7
Page: [610 - 613]
Pages: 4
DOI: 10.2174/1386207317666140313110334