A Convenient Synthesis of New 2-Cyanomethylthieno[3,2-e][1,2,4]- triazolo[1,5-c]pyrimidine Derivatives
Dhiab Jabli, Khaireddine Dridi and Mohamed L. El Efrit
Affiliation: Laboratory of Organic Chemistry, Department of Chemistry, Faculty of Sciences, El Manar University, El Manar II, Tunis 1060, Tunisia and Department of Chemistry, College of Sciences and Arts, Qassim University, Al-Rass, 53, Kingdom of Saudi Arabia.
Keywords: 2-Aminothiophene-3-carbonitrile, iminoethers, iminithieopyrimidin-3-ylamine, cyanoacetic acid hydrazide,
A new series of 2-cyanomethylthienotriazolopyrimidines has been synthesized in good yield through a facile
method using substituted aminothiophene-3-carbonitrile as building block and cyanoacetic acid hydrazide as reagent in
one framework. The structure of the synthesized compounds was established on the basis of their mass and spectral data.
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