Feasibility of Increased Navy Bean Powder Consumption for Primary and Secondary Colorectal Cancer Prevention
Erica C. Borresen,
Kerry A. Gundlach,
Regina J. Brown,
Elizabeth P. Ryan.
Introduction: Emerging evidence supports that increased consumption of dry beans (Phaseolus vulgaris L.) reduces both
the incidence and recurrence of adenomatous polyps or precancerous growths. Navy beans have been studied for dietary
colorectal cancer (CRC) chemoprevention in animal models. Our main objectives were to assess the feasibility of increased
navy bean consumption in adults with and without history of CRC and to achieve intake amounts associated with
Methods: Seven meals and six snacks were developed for both the absence and inclusion of cooked navy bean powder
(35grams/day). Sixteen healthy adults (7 non-cancer and 9 CRC survivors) completed the placebo-controlled, randomized,
single-blinded dietary intervention trial. Participants consumed one study-provided meal and snack daily for 28 days,
which accounted for approximately one-third of their total recommended caloric intake (meals = 202-483 kcal and snacks
= 194-401 kcal). Participants also recorded three-day dietary food logs each week.
Results: The addition of 35g of cooked navy bean powder (NBP) into foods provided 5-8% daily caloric intake. The compliance
to the meal and snack intervention ranged from 89-100%. Non-cancer participants in the NBP group had a significant
decrease in total caloric intake after week 4 (p0.0001). CRC survivors in the NBP group significantly increased total
fiber intake by week 4 (p0.0001).
Conclusions: NBP are feasible to include in meals for increased total fiber intake and for consuming the amount that is
associated with CRC chemoprevention outcomes. These findings warrant further evaluation of NBP consumption in clinical
nutrition trials for CRC control and prevention.
Keywords: Colorectal cancer, dietary fiber, dietary practices, functional foods, legumes, navy beans, nutrition, Phaseolus
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