Letters in Organic Chemistry

Miguel Yus  
Universidad de Alicante Apdo
Alicante
Spain

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Sodium Bromate/Sodium Hydrogen Sulfite: A New Catalyst for the Synthesis of Quinoxaline Derivatives

Author(s): Khalid M. Khan, Shafqat Hussain, Shahanaz Perveen, Fazal Rahim, Sammer Yousuf and Ejaz Hussain

Affiliation: H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan.

Keywords: Eco-friendly chemistry, high yield, quinoxaline, NaBrO3/NaHSO3 in water.

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Abstract:

Treatment of 1,2-phenylenediamine with benzil analogs in the presence of a mixture of sodium bromate/ sodium hydrogen sulfite in water gave the corresponding quinoxalines in high yields. The method is eco-friendly due to use of water instead of other hazardous organic solvents.

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Article Details

VOLUME: 11
ISSUE: 6
Page: [426 - 431]
Pages: 6
DOI: 10.2174/1570178611666140304000936