Sodium Bromate/Sodium Hydrogen Sulfite: A New Catalyst for the Synthesis of Quinoxaline Derivatives
Khalid M. Khan, Shafqat Hussain, Shahanaz Perveen, Fazal Rahim, Sammer Yousuf and Ejaz Hussain
Affiliation: H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan.
Keywords: Eco-friendly chemistry, high yield, quinoxaline, NaBrO3/NaHSO3 in water.
Treatment of 1,2-phenylenediamine with benzil analogs in the presence of a mixture of sodium bromate/
sodium hydrogen sulfite in water gave the corresponding quinoxalines in high yields. The method is eco-friendly due to
use of water instead of other hazardous organic solvents.
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