Chiral separation at nano scale is gaining importance in drugs development, proteomic, genomic and environmental
sciences. Generally, traces of drugs are found in our body for several weeks. These cannot be detected by conventional
analytical techniques. The present article discusses the advances in chiral resolution at nano scale using nano liquid
chromatography (NLC) and nano capillary electrophoresis (NCE). The instrumentation, chiral selectors, mechanisms of
chiral recognition and future challenges and prospectives have been discussed.
Keywords: Challenges and prospectives, chiral recognition mechanisms, chiral separations, nano capillary electrophoresis
(NCE), nano liquid chromatography (NLC).
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