Current Chromatography

Pavel N. Nesterenko
Australian Centre for Research on Separation Science (ACROSS)
School of Chemistry, University of Tasmania
Private Bag 75
Hobart, TAS 7001


Recent Trends in Chiral Separations by Nano Liquid Chromatography and Nano Capillary Electrophoresis

Author(s): Imran Ali, Zeid A. Al-Othman, Abdulrahman Al-Warthan and Hassan Y. Aboul-Enein

Affiliation: Department of Chemistry, Jamia Millia Islamia (Central University), New Delhi-110025, India.

Keywords: Chiral separations, nano liquid chromatography (NLC), nano capillary electrophoresis (NCE), chiral recognition mechanisms, Challenges and prospectives.


Chiral separation at nano scale is gaining importance in drugs development, proteomic, genomic and environmental sciences. Generally, traces of drugs are found in our body for several weeks. These cannot be detected by conventional analytical techniques. The present article discusses the advances in chiral resolution at nano scale using nano liquid chromatography (NLC) and nano capillary electrophoresis (NCE). The instrumentation, chiral selectors, mechanisms of chiral recognition and future challenges and prospectives have been discussed.

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Article Details

Page: [81 - 89]
Pages: 9
DOI: 10.2174/2213240601666140301001948