Current Chromatography

Pavel N. Nesterenko
Australian Centre for Research on Separation Science (ACROSS)
School of Chemistry, University of Tasmania
Private Bag 75
Hobart, TAS 7001


Recent Trends in Chiral Separations by Nano Liquid Chromatography and Nano Capillary Electrophoresis

Author(s): Imran Ali, Zeid A. Al-Othman, Abdulrahman Al-Warthan, Hassan Y. Aboul-Enein.


Chiral separation at nano scale is gaining importance in drugs development, proteomic, genomic and environmental sciences. Generally, traces of drugs are found in our body for several weeks. These cannot be detected by conventional analytical techniques. The present article discusses the advances in chiral resolution at nano scale using nano liquid chromatography (NLC) and nano capillary electrophoresis (NCE). The instrumentation, chiral selectors, mechanisms of chiral recognition and future challenges and prospectives have been discussed.

Keywords: Challenges and prospectives, chiral recognition mechanisms, chiral separations, nano capillary electrophoresis (NCE), nano liquid chromatography (NLC).

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Article Details

Year: 2014
Page: [81 - 89]
Pages: 9
DOI: 10.2174/2213240601666140301001948