Chronic Obstructive Pulmonary Disease (COPD), being a major cause of morbidity and mortality worldwide, is
a major problem for public health. It is predicted that its burden will continuously expand over the next years. This article
is an up-to-date review of both non-pharmacologic and pharmacologic management of COPD, which is now based on
new staging systems, able to predict prognosis and the response to different treatment approaches. Non-pharmacologic
therapies, such as smoking cessation, vaccinations and pulmonary rehabilitation are covered briefly. Current
pharmacologic management covers short acting beta-agonists (SABA), short acting muscarinic antagonists (SAMA), long
acting beta agonists (LABA), long acting antimuscarinics (LAMA), inhaled corticosteroids (ICS), LABA/ICS
combinations, xanthines, specific phosphodiesterase 4 (PDE4) inhibitors and oxygen therapy.