Quinoline – a Promising Fragment in the Search for New Antimalarials
Beata Gryzło and Katarzyna Kulig
Affiliation: Department of Physicochemical Drug Analysis, Department of Pharmaceutical Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
Malaria continues to be a potentially fatal threat to almost half of the world's population. In the present review,
efforts have been made to provide a literature concerning the study of quinoline as a privilege structure for search of new
malarials. The review covers advances in that field made in few last years.
Keywords: Antimalarials, antimicrobial activity, drug design, hybrid molecules, malaria, plasmodium falciparum, quinoline.
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