Mini-Reviews in Medicinal Chemistry


Quinoline – a Promising Fragment in the Search for New Antimalarials

Author(s): Beata Gryzło and Katarzyna Kulig

Affiliation: Department of Physicochemical Drug Analysis, Department of Pharmaceutical Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.


Malaria continues to be a potentially fatal threat to almost half of the world's population. In the present review, efforts have been made to provide a literature concerning the study of quinoline as a privilege structure for search of new malarials. The review covers advances in that field made in few last years.

Keywords: Antimalarials, antimicrobial activity, drug design, hybrid molecules, malaria, plasmodium falciparum, quinoline.

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Article Details

Page: [332 - 344]
Pages: 13
DOI: 10.2174/1389557514666140220123226