Mini-Reviews in Medicinal Chemistry


Bioactive Natural Compounds from the Mangrove Endophytic Fungi

Author(s): Kui-Wu Wang, Shi-Wei Wang, Bin Wu and Ji-Guang Wei

Affiliation: School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, China.


In recent years, mangrove endophytic fungi are increasingly attracting attention of the pharmaceutical community as they produce a wide variety of metabolites that are structurally unique and pharmacologically active. Previous chemical investigation of mangrove fungi resulted in the discovery of various bioactive secondary metabolites including terpenes, chromones, coumarins, polyketides, alkaloids and peptides with diverse structural features. The present report reviews the papers, which have appeared in the literature till now, concerning the isolation, structural elucidation, and biological activities of the secondary metabolites from mangrove endophytic fungi.

Keywords: Biological activities, mangrove endophytic fungi, metabolites, structure.

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Article Details

Page: [370 - 391]
Pages: 22
DOI: 10.2174/1389557514666140220122829