Leishmaniasis is a parasitic disease caused by Leishmania, transmitted by the bite of some sandfly species. It is
endemic in 88 countries throughout the world. Pentavalent antimonials are the standard therapy for leismaniasis. Saffron
(crocus sativus) belongs to the iridaceae family. This paper will outline the benefits and challenges of repurposing saffron
for treating leishmaniasis.
Keywords: Crocus sativus, cardiotoxicity, leishmaniasis, saffron, pathogenesis, treatment.
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