Recent Patents on Regenerative Medicine


Neurogenesis from Stem Cells

Author(s): Veronica R. Fortino, Devon Pawley, Nastasja Ecker, Zenith Acosta, Juan A. Kochen and Herman S. Cheung

Affiliation: Miami VA Medical Center, 1201 NW 16th Street, Miami, FL 33125, USA.


This review discusses the present field of neurogenesis using adult stem cells. The authors highlight different methods of differentiating adult stem cells into neural cells: Growth factor and chemical induction, transfection, scaffold and/or 3D culture, and bioreactor and external stimuli. These different methods will be discussed using relevant patents and recent (< 5 year) scientific literature. Additionally, the authors present where they believe the future of neurogenesis from stem cells is headed - the use of neural crest stem cells as the ideal cell source for neurogenesis.

Keywords: Differentiation, neural crest stem cells, neurogenesis, neuro-induction, stem cells.

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Article Details

Page: [16 - 33]
Pages: 18
DOI: 10.2174/2210296504666140214200150