Recent Patents on Regenerative Medicine


Neurogenesis from Stem Cells

Author(s): Veronica R. Fortino, Devon Pawley, Nastasja Ecker, Zenith Acosta, Juan A. Kochen and Herman S. Cheung

Affiliation: Miami VA Medical Center, 1201 NW 16th Street, Miami, FL 33125, USA.

Keywords: Differentiation, neural crest stem cells, neurogenesis, neuro-induction, stem cells.


This review discusses the present field of neurogenesis using adult stem cells. The authors highlight different methods of differentiating adult stem cells into neural cells: Growth factor and chemical induction, transfection, scaffold and/or 3D culture, and bioreactor and external stimuli. These different methods will be discussed using relevant patents and recent (< 5 year) scientific literature. Additionally, the authors present where they believe the future of neurogenesis from stem cells is headed - the use of neural crest stem cells as the ideal cell source for neurogenesis.

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Article Details

Page: [16 - 33]
Pages: 18
DOI: 10.2174/2210296504666140214200150