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Protein & Peptide Letters
ISSN (Print): 0929-8665
ISSN (Online): 1875-5305
Epub Abstract Ahead of Print
DOI: 10.2174/0929866521666140212111059      Price:  $95

Phosphorylation of HPr by HPr Kinase in Gluconobacter oxydans 621H

Author(s): Ping Zhang, Yushu Ma, Fengqing Wang and Dongzhi Wei
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DNA sequencing has revealed that Gluconobacter oxydans may contain an incomplete phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS), but the function of individual members of the system remains unknown. Here we demonstrated that the predicted histidine protein HPr, an essential component of PTS, can be phosphorylated by a predicted HPr kinase in G. oxydans, where Ser54 in HPr is the site responsible for such a phosphorylation. The discovery implies that G. oxydans may regulate PTS activity in a way similar to that identified in some Gram-positive bacteria with low GC content
State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, China