Lung Function In Health And Disease: Basic Concepts of Respiratory Physiology and Pathophysiology

Indexed in: Book Citation Index, Science Edition, EBSCO.

This reference presents basic concepts relevant to respiratory function in normal and diseased states.The volume stresses a quantitative approach to physical parameters used as indicators of normal ...
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Respiration at Rest and During Exercise at Sea Level and High Altitude

Pp. 215-232 (18)

Camillo Peracchia

Abstract

This chapter describes the physiological changes that occur when the organism is subjected to physical exercise, from resting state, at sea level and at high altitude. In particular, it focuses on compensatory mechanisms that regulate major respiratory functions, such as: gas exchange, ventilation-perfusion distribution, tissue oxygenation, pulmonary and systemic circulation, and acid-base balance. In addition, mechanisms involved in acclimatization to high altitude, acute and chronic mountain sickness, and adaptation to high altitude are briefly described.

Keywords:

Acid-Base Balance, Acute Mountain-Sickness, Alkalosis, Chronic Mountain-Sickness, Exercise, High-Altitude Acclimatization, High-Altitude Adaptation, High-Altitude Oxygen-Pressure, Hypocapnia, Hypoxia, Hypoxic Vasoconstriction, Joint Receptors, Metaboreceptors, Pulmonary Circulation, Pulmonary Edema, Pulmonary Hypertension, Shunt Fraction, Systemic Circulation, Ventilation-Perfusion Distribution, Ventilation-Perfusion Maldistribution.

Affiliation:

Department of Pharmacology and Physiology University of Rochester, School of Medicine and Dentistry 601 Elmwood Ave. Rochester, NY 14642-8711 USA