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Current Organic Synthesis

Editor-in-Chief

ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Synthesis of Asymmetric Diaryl Sulfides by SNAr Reaction of Substituted Nitrobenzene with Aryl Disulfides

Author(s): Naoki Enjo, Rong Lu and Tetsuo Miyakoshi

Volume 10, Issue 6, 2013

Page: [961 - 968] Pages: 8

DOI: 10.2174/157017941006140206105221

Price: $65

Abstract

A series of sulfides was successfully synthesized from nitroarenes by SNAr reaction via elimination of a nitro or phenylsulfonyl group. The SNAr reaction mechanism is found to depend on the position and type of substituents, and the effect of two-electron withdrawing groups was also examined.

Keywords: Sulfide, SNAr reaction, nitro group, aryl disulfide.


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