Current Organic Synthesis

Eduardo A. Castro
Universidad Nacional de La Plata
Buenos Aires
Argentina

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A Facile and Quick Synthesis of 9-aryl-substituted-acridines Mediated by DMP

Author(s): George Bratulescu

Affiliation: University of Craiova, Faculty of Chemistry, 13 A.I. Cuza, 200585 Craiova, Romania.

Keywords: Aromatic acids, acridine, bernthsen reaction, diphenylamine, DMP, water scavenger.

Abstract:

An unexpected three components reaction was developed for acridine synthesis in solvent free medium. The reaction is carried out with commercial reagents using of microwaves in a heterogeneous medium in presence of zinc chloride and 2,2-dimethoxypropane (DMP) as water scavenger. Principal advantages of the method are: short time, high yields and easy work-up.

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Article Details

VOLUME: 10
ISSUE: 6
Page: [947 - 950]
Pages: 4
DOI: 10.2174/157017941006140206104352