Abstract
α-Helixes are important structural motifs of protein three dimension structures and are largely involved in protein- protein interactions. This review covers the recent advances of the peptide stabilizing methodologies and introduces their applications in cancer research.
Keywords: Cancer therapy, protein-protein interaction, stapled peptide, α-helix.
Current Medicinal Chemistry
Title:Peptides-Staple Method Development and Its Application in Cancer Therapy
Volume: 21 Issue: 21
Author(s): Q.Z. Zhang, Y. Tian, Y.Z. Lao and Z.-G. Li
Affiliation:
Keywords: Cancer therapy, protein-protein interaction, stapled peptide, α-helix.
Abstract: α-Helixes are important structural motifs of protein three dimension structures and are largely involved in protein- protein interactions. This review covers the recent advances of the peptide stabilizing methodologies and introduces their applications in cancer research.
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Cite this article as:
Zhang Q.Z., Tian Y., Lao Y.Z. and Li Z.-G., Peptides-Staple Method Development and Its Application in Cancer Therapy, Current Medicinal Chemistry 2014; 21 (21) . https://dx.doi.org/10.2174/0929867321666140205130835
DOI https://dx.doi.org/10.2174/0929867321666140205130835 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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