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Current Organic Chemistry
ISSN (Print): 1385-2728
ISSN (Online): 1875-5348
VOLUME: 18
ISSUE: 9
DOI: 10.2174/1385272819666140201003050      Price:  $58









Reactions of 1,2- & 1,4-dihydropyridines

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Author(s): Sunil K. Singh and Vivek K. Sharma
Pages 1159-1207 (49)
Abstract:
This review provides a comprehensive compilation of available literature concerning the reactions of 1,2- & 1,4- dihydropyridines, which have opened new frontiers in the area of synthetic and medicinal chemistry. These reactions mainly include cycloaddition, 1,3-Dipolar cycloaddition, alkoxy halogenation, diamination, hydroxyamination, oxidation, hydroxylation, photooxygenation reaction, nucleophilic addition, cyclization, electrophilic substitution, multicomponent reactions (MCRs) and rearrangement reactions. 1,4-Dihydropyridine has also been used in hydrogen transfer reactions as a synthetic NADH model for the reduction of several important molecules in excellent yields.
Graphical Abstract:
Keywords:
1, 2- 1, 4-Dihydropyridines, aromatization, cycloaddition, diamination, oxidation, oxyselenation, photodimerisation, rearrangement.
Affiliation:
Department of Chemistry, Kirori Mal College, University of Delhi, Delhi-110 007, India.