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Letters in Organic Chemistry
ISSN (Print): 1570-1786
ISSN (Online): 1875-6255
VOLUME: 11
ISSUE: 5
DOI: 10.2174/1570178611666140124000908      Price:  $58









Enantioselective Transfer Reaction of Phenyl to Aldehydes Using LProline- Derived Amino Alcohols as Chiral Ligands

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Author(s): Yongmin Liu, Rongcheng Bo, Nan Wu, Yuehua Qiao, Yong Li, Hui Wu and Zhou Xu
Pages 356-360 (5)
Abstract:
((S)-1-(1,3,5-trimethyl)benzylpyrrolidin-2-yl)diphenylmethanol (1d) was found to be an effective chiral ligand in the asymmetric transfer reaction of phenyl to aldehydes to give the corresponding adducts in excellent enantioselectivity (up to 98% ee) with very high yields (up to 99%).
Keywords:
Tertiary amino alcohol, transfer reaction, phenylboronic acid, diethyl zinc, diarylmethanols.
Affiliation:
Department of Chemistry, Xuzhou Medical College, Xuzhou 221004, P.R. China.