Endocrine, Metabolic & Immune Disorders-Drug Targets

(Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders)

Emilio Jirillo  
Universitá degli Studi di Bari
Dipartimento di Clinica Medica
Immunologia e Malattie Infettive
Sezione di Microbiologia e Immunologia
Piazza Giulio Cesare-Policlinico


Immunopharmacology of the Main Herbal Supplements: A Review

Author(s): Angelo P. Amico, Annamaria Terlizzi, Sabino Damiani, Maurizio Ranieri, Marisa Megna and Pietro Fiore

Affiliation: Physical Medicine and Rehabilitation Unit, Neuroscience and Sense Organs Department, “Aldo Moro” University of Bari, Policlinico, Piazza Giulio Cesare 11, 70124 Bari, Italy.


It is debated whether the use of herbal supplements in endurance sports, in order to have a better performance, is correct or not, from the perspective of both as safety and as effectiveness. In this review we try to find out if the most common herbal supplements (Echinacea, Rhodiola, Ginseng) are effective in the improvement of performance or in the modulation of the immune system. According to the results of our review, the prevalent effect is adaptogenic rather than ergogenic, with a better tolerance of the exercise induced stress, related to enhancement of the whole immune system and decrease of the oxidative damage.

Keywords: Adaptogenic, echinacea, ginseng, herbal supplements, immune system, performance, rhodiola.

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Article Details

Page: [283 - 288]
Pages: 6
DOI: 10.2174/1871530314666140123152024