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Recent Patents on Cardiovascular Drug Discovery
ISSN (Print): 1574-8901
ISSN (Online): 2212-3962
Epub Abstract Ahead of Print
DOI: 10.2174/1574890109666140123121301      Price:  $140

Patents and Heart Valve Surgery – III: Percutaneous Heart Valves

Author(s): Faisal H. Cheema, Mona Ascha, Mohammad Bin Pervez, Ayesha Mannan, Alex P. Kossar and Gianluca Polvani
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Advancements in technology for the treatment of valvularcardiac diseases seek to provide solutions for high risk patients in the form of percutaneous valve insertion for patients with complicated valvular disease not amenable to more traditional options. Within the last decade, cardiac valves designed for percutaneous insertion have emerged rapidly as a treatment option for valvular disease. This procedure serves as an alternative to open heart surgery, which is more invasive and requires longer ICU stay. Thus, the percutaneous valve insertion procedure has been used on older, frailer patients who are poor candidates for open heart surgery. Designs for percutaneous valve insertion systems have been in development for decades, but have only recently been approved by the FDA for use. Important considerations include stent design, valve design, balloon catheter design, and deployment method
Director of Clinical Research and Innovations, Division of Cardiac Surgery, Department of Surgery, University of Maryland School of Medicine, 110 S Paca Street, 7th Floor, Baltimore, MD, 21201, USA &Laboratorio di IngegneriaTissutaleCardiovascolare, Centro CardiologicoMonzino - IRCCS, viaPAREA 4, 20138, Milan, Italy