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Endocrine‚ Metabolic & Immune Disorders-Drug Targets
(Formerly Current Drug Targets - Immune‚ Endocrine & Metabolic Disorders)
ISSN (Print): 1871-5303
ISSN (Online): 2212-3873
VOLUME: 14
ISSUE: 1
DOI: 10.2174/1871530314666140121145800









Refractory Proctocolitis in the Exclusively Breast-Fed Infants

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Author(s): Marina Atanaskovic-Markovic
Pages 63-66 (4)
Abstract:
The arm of this review was to help general pediatricians and primary care physicians in diagnosing and managing cow’s milk protein allergy in exclusively breast-fed infants.

Allergic proctocolitis is a cause of rectal bleeding in exclusively breast-fed infants aged from 1 to 6 months.It is due to cow’s milk protein transferred via breast milk. Diagnosis is based on clinical features and recovery after dietetic therapy. Rectal bleeding generally resolves within 72-96 hours of cow’s milk protein maternal avoidance. Most infants tolerate cow’s milk by their first birthday.

Keywords:
Allergic proctocolitis, α-S1-casein, β-lactoglobulin, blood streaked stool, breast-fed infants, cow’s milk proteins, non-IgE mediated immunologic reactions.
Affiliation:
University Children's Hospital, Medical Faculty University of Belgrade, Serbia.