Endocrine, Metabolic & Immune Disorders-Drug Targets

(Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders)

Emilio Jirillo  
Universitá degli Studi di Bari
Dipartimento di Clinica Medica
Immunologia e Malattie Infettive
Sezione di Microbiologia e Immunologia
Piazza Giulio Cesare-Policlinico


Breast-Milk Characteristics Protecting Against Allergy

Author(s): Federica Minniti, Pasquale Comberiati, Daniel Munblit, Giorgio L. Piacentini, Elisa Antoniazzi, Laura Zanoni, Attilio L. Boner and Diego G. Peroni

Affiliation: Department of Pediatrics, G.B. Rossi Polyclinic, Piazzale L.A. Scuro 10, 37134 Verona, Italy.


Breast milk and colostrum are the first feeding sources for a child, providing nutrients, growth factors and immunological components, which are crucial for the newborn’s correct development and health. Length of exclusive breastfeeding and time of solid foods introduction is a key factor that may influence allergy development. There is an emerging evidence of a relationship between breastfeeding, milk composition and lower risk of chronic diseases, such as diabetes, obesity, hypertension and allergies. This review examines current evidence regarding humoral and cellular characteristics of breast-milk, and potential role of environment, maternal diet and breastfeeding on the allergy development in children.

Keywords: Allergy, atopy, breast-milk, breastfeeding, cytokines, environment, immunoglobulin, nutrients.

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Article Details

Page: [9 - 15]
Pages: 7
DOI: 10.2174/1871530314666140121145045