Abstract
The high-throughput screening core at the University of Minnesota is part of the Institute for Therapeutics Discovery and Development (ITDD), a comprehensive drug discovery and development center. The Institute provides scientific services to both academic and business communities and supports translational medicine via collaborations and contractual work. The ITDD is well-known for its broad range of screening capabilities and offers extensive medicinal chemistry expertise along with GMP scale-up and pre-clinical pharmacology support.
Keywords: Drug development, drug discovery, good manufacturing practices (GMP), high throughput screening (HTS), medicinal chemistry, pharmacology, scale-up, translational science.
Combinatorial Chemistry & High Throughput Screening
Title:From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota
Volume: 17 Issue: 3
Author(s): Peter I. Dosa, Gunda I. Georg, Vadim J. Gurvich, Jon E. Hawkinson, Michael A. Walters and Henry L. Wong
Affiliation:
Keywords: Drug development, drug discovery, good manufacturing practices (GMP), high throughput screening (HTS), medicinal chemistry, pharmacology, scale-up, translational science.
Abstract: The high-throughput screening core at the University of Minnesota is part of the Institute for Therapeutics Discovery and Development (ITDD), a comprehensive drug discovery and development center. The Institute provides scientific services to both academic and business communities and supports translational medicine via collaborations and contractual work. The ITDD is well-known for its broad range of screening capabilities and offers extensive medicinal chemistry expertise along with GMP scale-up and pre-clinical pharmacology support.
Export Options
About this article
Cite this article as:
Dosa I. Peter, Georg I. Gunda, Gurvich J. Vadim, Hawkinson E. Jon, Walters A. Michael and Wong L. Henry, From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota, Combinatorial Chemistry & High Throughput Screening 2014; 17 (3) . https://dx.doi.org/10.2174/1386207317666140109122033
DOI https://dx.doi.org/10.2174/1386207317666140109122033 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
Call for Papers in Thematic Issues
Artificial Intelligence Methods for Biomedical, Biochemical and Bioinformatics Problems
Recently, a large number of technologies based on artificial intelligence have been developed and applied to solve a diverse range of problems in the areas of biomedical, biochemical and bioinformatics problems. By utilizing powerful computing resources and massive amounts of data, methods based on artificial intelligence can significantly improve the ...read more
Eco-friendly Agents for Biological Control of Pathogenic Diseases
The discovery of an alternative biological approach to disease management includes work on medicinal products derived from natural sources as a starting point for the development of eco-friendly agents for these diseases and the injuries they cause, as well as reducing human contact with hazardous chemicals and their residues. We ...read more
Emerging trends in diseases mechanisms, noble drug targets and therapeutic strategies: focus on immunological and inflammatory disorders
Recently infectious and inflammatory diseases have been a key concern worldwide due to tremendous morbidity and mortality world Wide. Recent, nCOVID-9 pandemic is a good example for the emerging infectious disease outbreak. The world is facing many emerging and re-emerging diseases out breaks at present however, there is huge lack ...read more
Exploring Spectral Graph Theory in Combinatorial Chemistry
Scope of the Thematic Issue: Combinatorial chemistry involves the synthesis and analysis of a large number of diverse compounds simultaneously. Traditional methods rely on brute force experimentation, which can be time-consuming and resource-intensive. Spectral Graph Theory, a branch of mathematics dealing with the properties of graphs in relation to the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Recent Advances in the Design of Cathepsin S Inhibitors
Current Topics in Medicinal Chemistry Impact of Diabetes in COVID-19 Associated Mucormycosis and its Management: A Non-Systematic Literature Review
Current Diabetes Reviews An Overview of Drug Screening Using Primary and Embryonic Stem Cells
Combinatorial Chemistry & High Throughput Screening Review on the Clinical Pharmacology of Hydroxychloroquine Sulfate for the Treatment of COVID-19
Current Drug Metabolism Painful Peripheral Neuropathies
Current Neuropharmacology Pharmacological Management of PDA: Oral Versus Intravenous Medications
Current Clinical Pharmacology Imaging Markers of Neurologic Damage in COVID-19: A Systematic Review
Current Medicinal Chemistry Graphical Abstracts
Current Organic Chemistry Transposable Elements and their Use for Target Site Specific Gene Delivery
Current Pharmacogenomics Current Overview on the Usage of Poly(ADP-ribose)polymerase (PARP) Inhibitors in Treating Cancer
Clinical Cancer Drugs Activatable Optical Probes for the Detection of Enzymes
Current Organic Synthesis Peptide-based Vaccines in the Treatment of Specific Allergy
Current Drug Targets - Inflammation & Allergy 3D-QSAR Approaches in Drug Design: Perspectives to Generate Reliable CoMFA Models
Current Computer-Aided Drug Design Total Phenolic Content and In vitro Antioxidant Activity of Endophytic Fungi Isolated from Calotropis procera L.
Current Bioactive Compounds Synthesis, <i>In Vitro</i> Evaluation, Molecular Docking and DFT Studies of Some Phenyl Isothiocyanates as Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry Computational Approaches for the Discovery of Cysteine Protease Inhibitors Against Malaria and SARS
Current Computer-Aided Drug Design Off-label Uses of Selective Serotonin Reuptake Inhibitors (SSRIs)
Current Neuropharmacology Ether Lipids as Anticancer Agents: Focus on Non-Phosphorus Cationic Glycerolipids
Mini-Reviews in Medicinal Chemistry An Insight into the Immunomodulatory Effects of Probiotics in the Prevention of COVID-19 Disease
Current Biotechnology Synthesis, SAR and Biological Evaluation of Natural and Non-natural Hydroxylated and Prenylated Xanthones as Antitumor Agents
Medicinal Chemistry