From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota
Peter I. Dosa, Gunda I. Georg, Vadim J. Gurvich, Jon E. Hawkinson, Michael A. Walters and Henry L. Wong
Affiliation: Institute for Therapeutics Discovery and Development, 717 Delaware St. SE, Minneapolis, MN 55414, USA.
Keywords: Drug development, drug discovery, good manufacturing practices (GMP), high throughput
screening (HTS), medicinal chemistry, pharmacology, scale-up, translational science.
The high-throughput screening core at the University of Minnesota is part of the Institute for
Therapeutics Discovery and Development (ITDD), a comprehensive drug discovery and development
center. The Institute provides scientific services to both academic and business communities and
supports translational medicine via collaborations and contractual work. The ITDD is well-known for its
broad range of screening capabilities and offers extensive medicinal chemistry expertise along with
GMP scale-up and pre-clinical pharmacology support.
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