Novel Approach for the Synthesis of Pyrrolo[2,1-c][1,4]Benzoxazines and Pyrrolo[1,2-a]Quinoxalines

Author(s): Tayebeh Sanaeishoar, Somayeh Adibi-Sedeh, Saghar Karimian.

Journal Name: Combinatorial Chemistry & High Throughput Screening

Volume 17 , Issue 2 , 2014

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Abstract:

An efficient synthesis of alkyl 4,5-dihydro-4-oxo-2-phenylpyrrolo[2,1-c][1,4]benzoxazine-3-carboxylates and alkyl 4,5-dihydro-4-oxo-2-phenylpyrrolo[1,2-a]quinoxaline-3-carboxylates is described. This involves a three-component reaction between o-aminophenols or o-phenylenediamine, acetylenic esters and β-nitrostyrene derivatives using p-toluene sulfonic acid as a catalyst.

Keywords: o-aminophenols, o-phenylenediamine, p-toluene sulfonic acid, pyrrolo[1, 2-a]quinoxaline, pyrrolo[2, 1-c][1, 4]benzoxazine, β- nitrostyrenes.

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Article Details

VOLUME: 17
ISSUE: 2
Year: 2014
Page: [157 - 161]
Pages: 5
DOI: 10.2174/1386207316666131227150430
Price: $58

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