CNS & Neurological Disorders - Drug Targets

(Formerly Current Drug Targets - CNS & Neurological Disorders)

Stephen D. Skaper  
Department of Pharmaceutical and Pharmacological Sciences
University of Padova
Padova
Italy

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Wnt Signaling Pathway in Schizophrenia

Author(s): Yanmin Peng, Yifeng Xu, Donghong Cui.

Abstract:

The Wnt signaling pathway is one of the crucial signaling pathways that regulate many aspects of central nervous system. In this review, we tempt to depict an overall picture of the Wnt signaling with its multitude of roles in schizophrenia. If the Wnt signaling pathway plays a crucial role in the pathogenesis of schizophrenia as we suggest, a better understanding of the Wnt pathway might contribute to developing new and more effective tools for diagnosis and treatment of schizophrenia.

Keywords: Adenomatous polyposis coli, glycogen synthase kinase-3, schizophrenia, Wnt signaling pathway.

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Article Details

VOLUME: 13
ISSUE: 5
Year: 2014
Page: [755 - 764]
Pages: 10
DOI: 10.2174/1871527312666131223113521
Price: $58