Derivatization Coupled to Chemiluminescence Detection

Author(s): George Z. Tsogas, Dimosthenis L. Giokas, Athanasios G. Vlessidis.

Journal Name:Current Analytical Chemistry

Volume 10 , Issue 3 , 2014

Graphical Abstract:


In this work, an overview of analytical methods employing derivatization reactions in chemiluminescence detection is presented. Method development, instrumental configurations and hyphenated manifolds, specifically designed or implemented to accommodate CL detection, along with their analytical applications for the determination of a wide variety of organic compounds such as biochemically active substances, pharmaceutical active compounds, environmental pollutants and food constituents, are summarized. The analytical merits of derivatization reactions in chemiluminescence analysis and their potential for the development of sensitive and selective methods are elucidated.

Keywords: Chemiluminescence, derivatization, liquid chromatography, capillary electrophoresis.

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Article Details

Year: 2014
Page: [305 - 319]
Pages: 15
DOI: 10.2174/1573411010999131219101823
Price: $58