Recent Advances in the Synthesis of Heterocycles from Oximes
Edgars Abele and Ramona Abele
Affiliation: Latvian Institute of Organic Synthesis, Riga, LV1006, Latvia.
This review demonstrates that oximes and their derivatives are valuable starting materials for the preparation of many classes
of heterocyclic compounds. The main group of reactions includes the cyclization of unsaturated oxime derivatives. Using these starting
materials pyrroles, isoxazoles, pyridines and isoquinolines were prepared. Some heterocyclic systems (for example, seven-membered
rings) were obtained using the classical Beckmann rearrangement and novel reagents and conditions.
Keywords: Four-membered heterocycles, five-membered heterocycles, large-membered rings, oximes, six-membered heterocycles, threemembered
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