Osteoporotic Fracture Healing: Potential Use of Medicinal Plants from the Tropics

Author(s): Mohd Azri Abdul Jalil, Ahmad Nazrun Shuid, Norliza Muhammad.

Journal Name: Current Drug Targets

Volume 14 , Issue 14 , 2013

Abstract:

With improvements in living standards and healthcare, life expectancy has been increasing dramatically in most parts of the world. These situations lead to the increase in the reported cases of geriatrics-related diseases such as hypogonadal osteoporosis with skeletal fracture being the ultimate outcome, which eventually causes significant morbidity and mortality. The deficient gonadal hormones, which are the main cause of hypogonadal osteoporosis, could be substituted with hormone replacement therapy to hinder bone loss. However, the artificial hormonal therapy has been linked to grievous conditions such as breast and prostate cancers. In view of the various adverse effects associated with conventional treatment, many researchers are now focusing on finding alternative remedies from nature. This article explores the possibilities of certain medicinal plants native to Malaysia that possess androgenic and antioxidant properties to potentially be used in the treatment of fracture due to osteoporosis in ageing people.

Keywords: Androgens, antioxidants, medicinal plants, osteoporosis, osteoporotic fracture.

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Article Details

VOLUME: 14
ISSUE: 14
Year: 2013
Page: [1651 - 1658]
Pages: 8
DOI: 10.2174/1389450114666131217113759
Price: $58

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