With improvements in living standards and healthcare, life expectancy has been increasing dramatically in most
parts of the world. These situations lead to the increase in the reported cases of geriatrics-related diseases such as hypogonadal
osteoporosis with skeletal fracture being the ultimate outcome, which eventually causes significant morbidity and
mortality. The deficient gonadal hormones, which are the main cause of hypogonadal osteoporosis, could be substituted
with hormone replacement therapy to hinder bone loss. However, the artificial hormonal therapy has been linked to grievous
conditions such as breast and prostate cancers. In view of the various adverse effects associated with conventional
treatment, many researchers are now focusing on finding alternative remedies from nature. This article explores the possibilities
of certain medicinal plants native to Malaysia that possess androgenic and antioxidant properties to potentially be
used in the treatment of fracture due to osteoporosis in ageing people.
Keywords: Androgens, antioxidants, medicinal plants, osteoporosis, osteoporotic fracture.
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