Recent Advances in Cinchona Alkaloid Catalysis for Enantioselective Carbon-Nitrogen Bond Formation Reactions

Author(s): Hiroaki Saito, Shinichi Miyairi.

Journal Name: Current Topics in Medicinal Chemistry

Volume 14 , Issue 2 , 2014

Become EABM
Become Reviewer

Abstract:

Organocatalysis and cooperative catalysis are fast growing research areas. In these fields, cinchona alkaloids and their derivatives play a major role. The ready availability of both pseudo-enantiomeric pairs from natural sources makes them outstanding catalysts for reactions including oxidation, alkylation, cycloaddition, and carbene insertion. This short review focuses on recent achievements in the field of asymmetric carbon-nitrogen atom bond formation reactions using cinchona alkaloids and their derivatives.

Keywords: Cinchona alkaloids, enantioselective, N–H bond, organocatalysis, carbene.

Rights & PermissionsPrintExport Cite as


Article Details

VOLUME: 14
ISSUE: 2
Year: 2014
Page: [224 - 228]
Pages: 5
DOI: 10.2174/1568026613666131213160228
Price: $58

Article Metrics

PDF: 23