Niobic Acid as a Recyclable Heterogeneous Catalyst for the Solvent-Free Synthesis of Substituted Benzimidazoles

Title:Niobic Acid as a Recyclable Heterogeneous Catalyst for the Solvent-Free Synthesis of Substituted Benzimidazoles

Volume: 1 Issue: 2

Author(s): Beatriz M. Vieira, Angelita M. Barcellos, Ricardo F. Schumacher, Eder J. Lenardao and Diego da Silva Alves

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Keywords: Aldehydes, atom-economic, benzimidazoles catalysis, condensation, green chemistry, heterogeneous, heterocycles, heterocycles, niobic acid, niobium, nitrogen compounds, phenylenediamine, solid catalyst.

Abstract: We describe here a simple method for the synthesis of several substituted benzimidazoles using niobic acid Nb₂O₅.5H₂O as heterogeneous catalyst and under solvent-free conditions. This new protocol is general and a range of aromatic and aliphatic aldehydes were condensed with o-phenylenediamine furnishing the corresponding 1,2-disubstituted benzimidazoles selectively in good yields. The catalyst was reused up four times giving the respective products in good yields but with a little decreasing in the selectivity.

Cite this article as:

Vieira M. Beatriz, Barcellos M. Angelita, Schumacher F. Ricardo, Lenardao J. Eder and Alves da Silva Diego, Niobic Acid as a Recyclable Heterogeneous Catalyst for the Solvent-Free Synthesis of Substituted Benzimidazoles, Current Green Chemistry 2014; 1 (2) . https://dx.doi.org/10.2174/2213346101666131212005735