Current Green Chemistry

György Keglevich
Budapest University of Technology and Economics


Niobic Acid as a Recyclable Heterogeneous Catalyst for the Solvent-Free Synthesis of Substituted Benzimidazoles

Author(s): Beatriz M. Vieira, Angelita M. Barcellos, Ricardo F. Schumacher, Eder J. Lenardao and Diego da Silva Alves

Affiliation: LASOL - CCQFA - Universidade Federal de Pelotas - UFPel - P.O. Box 354 - 96010-900, Pelotas, RS, Brazil.


We describe here a simple method for the synthesis of several substituted benzimidazoles using niobic acid Nb2O5.5H2O as heterogeneous catalyst and under solvent-free conditions. This new protocol is general and a range of aromatic and aliphatic aldehydes were condensed with o-phenylenediamine furnishing the corresponding 1,2-disubstituted benzimidazoles selectively in good yields. The catalyst was reused up four times giving the respective products in good yields but with a little decreasing in the selectivity.

Keywords: Aldehydes, atom-economic, benzimidazoles catalysis, condensation, green chemistry, heterogeneous, heterocycles, heterocycles, niobic acid, niobium, nitrogen compounds, phenylenediamine, solid catalyst.

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Article Details

Page: [136 - 144]
Pages: 9
DOI: 10.2174/2213346101666131212005735
Price: $58