Diagnostic Performance of Magnetic Resonance Cholangiopancreatography (MRCP) for Biliopancreatic Cancer
Sandy Hassan Hossary, Ashraf Anas Zytoon, Mohamed Eid, Ahmed Hamed, Mohamed Sharaan and Ahmed Abd El-Maguid Ebrahim
Affiliation: Doctorate of Diagnostic Radiology and Nuclear Medicine, Japan; Fellowship of Japanese Radiology Society, Doctorate of Diagnostic and Interventional Radiology, Egypt.
Keywords: MRCP, biliary cancer, pancreatic cancer.
Introduction: MRCP has achieved widespread success as a diagnostic tool for biliopancreatic cancer.
Aim of the study: is to assess the diagnostic quality and overall accuracy of MRCP techniques for the evaluation of
Patients and Methods: from 266 patients (115 male, 151 female; mean age 50), 63 suspected for biliary tree or pancreatic
diseases cancer and histopathologically confirmed, were enrolled in this study. MRCP protocols applied for imaging
of biliary and pancreatic tree were; T2-weighted Fast spin echo (FSE) sequence on the axial plane, three-dimensional, fatsuppressed,
heavily T2-weighted FSE sequence with multislab acquisition mode, two-dimensional thick single slab projectional
images, three-dimensional reconstruction algorithms.
Results: among the patients, jaundice and abdominal pain were the commonest clinical complaints. Three-dimensional,
fat-suppressed, heavily T2-weighted FSE sequence with multislab acquisition mode shows a significant (p<0.05) improvement
in accuracy to from 88.1% to 92.9% compared to two-dimensional thick single slab projectional images.
Moreover, there is a significant increase in sensitivity from 90.5% to 95.2% was seen; specificity, too, increased from
85.7% to 90.5%. Furthermore, Overall bile duct visualization with the 3D fat-suppressed, heavily T2 FSE with multislab
acquisition technique was rated significantly higher (mean score = 4.7) versus 2D thick single slab projectional images
(mean score= 4) (P < 0.05).
Conclusion: MRCP plays a critical role in the differential diagnosis with significant improvement in the accuracy of the
diagnosis of biliopancreatic cancer.
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