Current Neuropharmacology

T.E. Salt
University College London
Institute of Ophthalmology
London EC1V 9EL
UK

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Potential Effects of Cannabidiol as a Wake-Promoting Agent

Author(s): Eric Murillo-Rodriguez, Andrea Sarro-Ramirez, Daniel Sanchez, Stephanie Mijangos-Moreno, Alma Tejeda-Padron, Alwin Poot-Ake, Khalil Guzman, Elda Pacheco-Pantoja and Oscar Arias-Carrion

Affiliation: Laboratorio de Neurociencias Moleculares e Integrativas, Escuela de Medicina, Division Ciencias de la Salud, Universidad Anahuac Mayab, Carretera Merida-Progreso Km, 15.5, A.P. 96 Cordemex C.P. 97310, Merida, Yucatan, Mexico.

Keywords: Dopamine, hypothalamus, marijuana, sleep, sleepiness.

Abstract:

Over the last decades, the scientific interest in chemistry and pharmacology of cannabinoids has increased. Most attention has focused on Δ9-tetrahydrocannabinol (Δ9-THC) as it is the psychoactive constituent of Cannabis sativa (C. sativa). However, in previous years, the focus of interest in the second plant constituent with non-psychotropic properties, cannabidiol (CBD) has been enhanced. Recently, several groups have investigated the pharmacological properties of CBD with significant findings; furthermore, this compound has raised promising pharmacological properties as a wake-inducing drug. In the current review, we will provide experimental evidence regarding the potential role of CBD as a wake-inducing drug.

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Article Details

VOLUME: 12
ISSUE: 3
Page: [269 - 272]
Pages: 4
DOI: 10.2174/1570159X11666131204235805