Over the past decades DNA sequencing technologies have been improving in aspects like quality, read length,
runtimes and yields, all at a lower cost. Despite these improvements, genome assembly remains a challenge in genome sequencing
projects, especially when different sequencing platforms are used. At the present, there is no program that can
handle and assemble different sequencing technologies better than specialized software for each of them. Also, very few
protocols are available for merging results from different algorithms, technologies or both. We present GARM, (Genome
Assembler, Reconciliation and Merging) a pipeline to merge assemblies from different algorithms or sequencing technologies.
Keywords: Bioinformatics, genome assembly, genome reconciliation, genome merging, meta-assembly, next-generation sequencing.
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