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Current Cardiology Reviews
ISSN (Print): 1573-403X
ISSN (Online): 1875-6557
Epub Full Text Article
DOI: 10.2174/1573403X09666131202123646      Price:  $95

Transcatheter Heart Valves: Specific Characteristics and Potential Shortcomings

Author(s): J Blumenstein, A Van Linden, H Moellmann, T Walther and J Kempfert
During the past years TAVI has evolved to a standard technique for the treatment of high risk patients suffering from severe aortic stenosis. Worldwide the number of TAVI procedures is increasing exponentially. In this context both the transapical antegrade (TA) and the transfemoral retrograde (TF) approach are predominantly used and can be considered as safe and reproducible access sites for TAVI interventions. As a new technology TAVI is in a constant progress regarding the development of new devices. While in the first years only the Edwards SAPIEN™ and the Medtronic CoreValve™ prostheses were commercial available, recently additional devices obtained CE-mark approval and others have entered initial clinical trials. In addition to enhance the treatment options in general, the main driving factor to further develop new device iterations is to solve the drawbacks of the current TAVI systems: paravalvular leaks, occurrence of AV-blocks and the lack of full repositionability
Transapical, transfemoral, transcatheter aortic valve implantation, aortic valve stenosis
Department of Cardiac Surgery, Kerckhoff Heart-Center, Benekestrasse 2-8, 61231 Bad Nauheim, Germany