Polyphenols: A Nutraceutical Approach Against Diseases
Andrea P. B. Gollucke, Rogerio C. Peres, Odair A. Jr and Daniel A. Ribeiro
Affiliation: HEXALAB/UNISANTOS – Catholic University of Santos. Av. Conselheiro Nebias, 300. Santos-SP 11015-002. Brazil.
Polyphenols are abundant in red grapes and in their derived products, amongst other natural food sources.
These compounds are associated with the prevention of diseases caused by oxidative stress. The present review discusses
the action of grape polyphenols against diseases and the new polyphenol-rich products developed to be used as nutraceuticals.
Grape polyphenols demonstrated effects such as maintenance of endothelial function, increase in antioxidant capacity
and protection against LDL oxidation. Recent patents regarding polyphenols show a tendency to use a right-on-target
approach and the new patented products are aiming at preventing and treating specific diseases.
Keywords: Atherosclerosis, cardiovascular diseases, functional foods, flavonoids, grape juice.
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