Nanosilica chloride was prepared with modification of the surface by applying ultrasonic irradiation and has
been employed as an efficient, heterogeneous and effective catalyst in the preparation of 3,4- dihydropyrimidinones
(DHPMs) under solvent-free conditions. Simple workup procedure, short reaction time, and good to excellent yield of the
product, are other advantages of this catalyst.
Keywords: Nanosilica chloride, multicomponent reactions, ultrasonic irradiation, Biginelli reaction, dihydropyrimidinones,
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