Another Brick in the Wall: Innate Lymphoid Cells of the Intestine
Frann Antignano and Colby Zaph
Affiliation: Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, V6T1Z3, Canada.
Keywords: Helminth, infection, innate lymphocytes, intestine, protozoan.
Since the recent identification of the expanding innate lymphoid cell (ILC) family, there has been an explosion
of interest and research in the ontogeny, phenotype and function of these cells. In the intestine, ILCs are a significant
component of the immune cell repertoire in the steady state and several recent studies have identified critical roles for
ILCs in homeostasis and disease. In this review, ILC biology will be addressed in the context of intestinal homeostasis,
inflammation and immunity to intestinal infections.
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