Tuberculosis Treatment: The Search For New Drugs

Despite the high impact on human health caused by Tuberculosis (TB) infections worldwide, nearly 45 years have passed since a novel drug was introduced for its treatment. As MDR-TB and XDR-TB cases ...
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Anti-TB Evaluation of Marine Natural Products

Pp. 196-216 (21)

Marcus V.N. de Souza


The interest of marine natural products in the development of new drugs to treat tuberculosis began in the 1990s with compounds isolated and evaluated in both plant and animal sources becoming an important source of new anti-TB compounds that will be covered in this chapter.


Tuberculosis, Mycobacterium tuberculosis, natural products, sea, semi-synthesis, synthesis, analogues, treatment, multi-drug-resistant tuberculosis (MDR TB), extensive-drug-resistant tuberculosis (XDR TB), target, mechanism of action, biological evaluation, drug development.


Instituto de Tecnologia em Fármacos - Farmanguinhos, FioCruz - Fundação Oswaldo Cruz, R. Sizenando Nabuco, 100, Manguinhos, 21041-250, Rio de Janeiro, RJ, Brazil.