Graphene, a truly two-dimensional (2D) and fully Π-conjugated honeycomb network, exhibits many unique
physical and chemical properties that are interesting in a wide range of areas. Since its discovery in 2004, graphene has
been extensively studied in many different fields including nano-electronics, composite materials, energy research, catalysis
and so on. Based on the fascinating action of members in the carbon family, notably zero dimensional (0D) fullerenes
and one dimensional (1D) carbon nanotubes (CNTs) in biomedical areas, increasing number of reports have explored the
potential of graphene for different biomedical and biotechnical applications since 2008. This manuscript aims to provide a
summary of current research progress of graphene-based carbon materials in biosensing, drug (gene) delivery and tissue
engineering, and discusses the opportunities and challenges in this rapidly growing field.