Recent Patents on Nanotechnology

Eduardo Ruiz- Hitzky  
Department of New Architectures in Materials Chemistry
Materials Science Institute of Madrid


Synthesis and Characterization of Fe-Based Metal and Oxide Based Nanoparticles: Discoveries and Research Highlights of Potential Applications in Biology and Medicine

Author(s): Nguyen Viet Long, Cao Minh Thi, Yang Yong, Yanqin Cao, Haibo Wu and Masayuki Nogami

Affiliation: Shanghai Institute of Ceramics, Chinese Academy of Science, 1295, Dingxi Road, Shanghai 200050, China.

Keywords: Biology and medicine, biomedical applications, Fe3O4-based nanoparticles, Fe-based bimetallic nanoparticles, Febased core shell nanoparticles, Fe-based mixture nanoparticles, Fe-based nanoparticles, Fe-based nanostructures, hyperthermia, Iron metal, magnetic nanoparticles, magnetic properties, magnetic resonance imaging (MRI), nano fluids, α- and γ-Fe2O3 nanoparticles.


In this review, we have presented the controlled synthesis of Fe-based metal and oxide nanoparticles with large size by chemical methods. The issues of the size, shape and morphology of Fe nanoparticles are discussed in the certain ranges of practical applications in biology and medicine. The homogeneous nanosystems of Fe-based metal and oxide nanoparticles with various sizes and shapes from the nano-to-micro ranges can be used in order to meet the demands of the treatments of dangerous tumors and cancers through magnetic hyperthermia and magnetic resonance imaging (MRI). In this context, the polyhedral Fe-based metal and oxide nanoparticles having large size in the ranges from 1000 nm to 5000 nm can be potentially used in magnetic hyperthermia and MRI in the innovative drug delivery, diagnosis, treatment, and therapy of tumor and cancer diseases because of their very high bio-adaptability. We have suggested that high stability and durability of Fe-based metal and oxide nanoparticles are very crucial to recent magnetic hyperthermia and MRI technology. The roles of various Fe-based nanostructures are focused in biomedical applications of tumors and cancers diagnostics, targeted drug delivery, and magnetic hyperthermia. Finally, Fe-based, α-, β- and γ-Fe2O3, and Fe3O4-based nanoparticles are shortly discussed in various potential applications in catalysis, biology, and medicine.

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Article Details

Page: [52 - 61]
Pages: 10
DOI: 10.2174/1872210507666131117183008