Recent Advances in Immunotherapy for Allergic Diseases
David El-Qutob, Gemma Mencia and Enrique Fernandez-Caldas
Affiliation: Unit of Allergy, Hospital La Plana, Carretera Vila-Real-Burriana Km. 0.5 Vila-Real (Castellon) 12540, Spain.
Keywords: Allergoid, allergy, asthma, house dust mite, immunotherapy, parvalbumin, rhinitis.
Allergic diseases are a major health problem worldwide. The therapeutic approaches to treat allergic rhinitis
(AR) and allergic asthma (AA) fall in three major categories. The first step is allergen avoidance, or reduction of exposure
to the offending allergen(s). The second and most widely used therapeutic practice is the prescription of relevant medication
to reduce symptoms. The third therapeutic element is specific allergy vaccination, also known as allergen specific
immunotherapy. Allergen-specific immunotherapy (SIT) is the only etiologic treatment of allergic disorders that can alter
the natural course of the disease. In this review, recent advances in immunotherapy and relevant patents are presented.
General vaccine modifications could be applied for any type of allergen. New specific modifications in allergic vaccines
have been developed for a variety of allergies such as house dust mites, horse, cat, parvalbumin and from birch, ragweed
and parietaria pollen.
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