Therapeutic Proteins: A to Z

Author(s): Aykut Ozgur, Yusuf Tutar.

Journal Name: Protein & Peptide Letters

Volume 20 , Issue 12 , 2013

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Abstract:

In recent years, therapeutic proteins have become an important growing class of drugs in the pharmaceutics industry. The development of recombinant DNA technology has caused to appreciation of therapeutic value of many proteins and peptides in medicine. Currently, approximately 100 therapeutic proteins obtained approval from Food and Drug Administration (FDA) and they are widely used in the treatment of various diseases such as cancer, diabetes, anemia and infections. This paper will summarize the production processes, pharmaceuticals and physicochemical properties and important classes of therapeutic proteins with their potential use in clinical applications.

Keywords: Therapeutic proteins, recombinant DNA technologies, monoclonal antibodies, interferons, insulin and erythropoietin.

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Article Details

VOLUME: 20
ISSUE: 12
Year: 2013
Page: [1365 - 1372]
Pages: 8
DOI: 10.2174/092986652012131112125148
Price: $58

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