Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Michelle Prudhomme  
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex


Therapeutic Vaccines Explored in Patients with Non-Small Cell Lung Cancer

Author(s): Kui Ma and Ya H. Tang

Affiliation: LSU Health Sciences Center, School of Medicine, 1501 Kings Hwy, P.O. Box 33932, Shreveport, LA 71130, USA.

Keywords: Immunotherapy, MAGE-A3, MUC1, non-small cell lung cancer, tumor antigens, vaccine.


Traditional anti-cancer therapies (surgery, radiotherapy and chemotherapy) have limited effectiveness in curbing progression of advanced tumors. However, with advances in immunology and molecular biology in the last two decades, the prognosis of cancer immunotherapy has improved. An emerging therapy is the cancer vaccine as adjunctive therapy. The purpose of this paper is to review this therapeutic modality for non-small cell lung cancer.

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Article Details

Page: [256 - 264]
Pages: 9
DOI: 10.2174/18715206113136660378