Immunology of Pregnancy 2013

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Since a September, 1992, Nature article which read: “Can there be life without LIF?”, researchers now realize that the maternal immune system is both a foe (it can reject the conception) and a ...
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Part E: Debates on Immunotherapy for Recurrent Pregnancy Failure

Pp. 724-734 (11)

Gérard Chaouat


This chapter briefly summarizes the reasons which I put forwards at the time to discard tmost of the immunotherapy approach for recurrent pregnancy failure, and the recent developments which make me partly revise my opinion, since a safe and effective treatment might have been proposed.


Abortion, immunotherapy, history, concerns, cochrane, efficiency, inocuity, TNF, regulators.


Director of Research Emeritus, U976 INSERM /UMR 976 CNRS Saint Louis Hospital 75010, Paris France.