Immunology of Pregnancy 2013

Indexed in: Book Citation Index, Science Edition, EBSCO.

Since a September, 1992, Nature article which read: “Can there be life without LIF?”, researchers now realize that the maternal immune system is both a foe (it can reject the conception) and a ...
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Part B: Immunoregulation at the Interface by Placental Suppressor Factors

Pp. 525-535 (11)

Gérard Chaouat

Abstract

In this brief sub-chapter we review first quickly pregnancy specific proteins (which were at the time seen in a context of general dampening of maternal immune response) to discuss then anergy inducing placental factors and exosomes. We finish by dealing with placenta integrated retroviruses, and their immunosuppressive properties.

Keywords:

Placenta, Immunity, Suppression, Induction, IDO, HcG, PIF, EPF.PIBF, HLA-G, Factors, Anergy, Exosomes, IL-10, Retrovirus, Syncitin.

Affiliation:

Director of Research Emeritus, U976 INSERM /UMR 976 CNRS Saint Louis Hospital 75010, Paris France.