Coronary CT Angiography in the Diagnosis of Coronary Artery Disease
Zhonghua Sun, Yung-Liang Wan, I-Chang Hsieh, Yuan-Chang Liu and Ming-Shien Wen
Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou Healthy Aging Research Center, College of Medicine, Chang Gung University. 5 Fusing Rd, Kueishan Hsiang Taoyuan, 333, Taiwan
Keywords: Coronary artery disease, coronary CT angiography, diagnostic value, predictive value, plaque, atherosclerosis.
Coronary CT angiography is increasingly used in the diagnosis of coronary artery disease due to rapid technological
developments, which are reflected in the improved spatial and temporal resolution. High diagnostic accuracy has
been achieved with 64- and more slice CT scanners, and in selected patients, coronary CT angiography is considered a reliable
alternative to invasive coronary angiography. Quantifying the amount of coronary artery calcium with coronary CT
angiography has been widely accepted as a reliable non-invasive technique for predicting risk of future cardiac events.
Coronary CT angiography is able to detect variable densities in the coronary atherosclerotic plaques and demonstrate the
corresponding intraluminal changes due to presence of plaques, thus providing prognostic value of disease extent. Coronary
CT angiography is an accurate method to measure coronary bifurcation angles and demonstrate dimensional changes,
hence, providing relevant features of left coronary atherosclerosis. This article provides an overview of the diagnostic and
predictive value of coronary CT angiography in coronary artery disease.
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