Inflammatory bowel disease (IBD) is a chronic, immune-mediated disease of the gastrointestinal tract that develops in genetically
susceptible individuals. Questions about the role of infections in the development and exacerbations of inflammatory bowel disease
remain unanswered. Among numerous bacteria that have been linked to IBD, the most frequently associated is Clostridium difficile.
Clinical symptoms of C. difficile infection and an exacerbation of inflammatory bowel disease are often indistinguishable. In cases of diarrhea
in patients with IBD and C. difficile infection, antibiotic treatment is recommended. This review attempts to summarize C. difficile
infection’s epidemiology and clinical features and describes current evidence on treatment of C. difficile infection in children with IBD.
Keywords: Ulcerative colitis, Crohn's disease, CDI, IBD.
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